CURRICULUM VITAE

Professions: Systems Analyst, Corporate Development Manager, Researcher

Programming Languages Known: Fortran, Basic, PPL, C, Bliss, SQL, Perl, 5+ assembly languages

Long-term Objectives:

A. PUBLISHED PAPERS - Peer Reviewed

1. Gaziev, A. I., Podlutsky, A. Ja., Panfilov, B.M., Bradbury, R., "Dietary supplements of antioxidants reduce hprt mutant frequency in splenocytes of aging mice," Mutat Res. 338(1-6):77-86 (Oct., 1995).
2. Sirota, N. P., Bezlepkin V. G., Kuznetsova E. A., Lomayeva M. G., Milonova I. N., Ravin V. K., Gaziev A. I., Bradbury R. J., "Modifying effect in vivo of interferon alpha on induction and repair of lesions of DNA of lymphoid cells of gamma-irradiated mice," Radiat Res. 146(1):100-5 (Jul, 1996).
3. Ushakova, T., Melkonyan, H., Nikonova, L., Mudrik, N, Gogvadze, V., Zhukova, A., Gaziev, A. I., Bradbury, R., "The effect of dietary supplements on gene expression in mice tissues," Free Radic. Biol. Med. 20(3):279-84 (1996).
4. Gaziev, A. I., Sologub, G. R., Fomenko, L. A., Zaichkina S. I., Kosyakova, N. I., Bradbury R. J., "Carcinogenesis Effect of vitamin-antioxidant micronutrients on the frequency of spontaneous and in vitro gamma-ray-induced micronuclei in lymphocytes of donors: the age factor," Carcinogenesis 17(3):493-9 (Mar, 1996).
5. Ushakova, T., Melkonyan, H., Nikonova, L., Afanasyev, V., Gaziev, A. I., Mudrik N, Bradbury, R., Gogvadze V., "Modification of gene expression by dietary antioxidants in radiation-induced apoptosis of mice splenocytes," Free Radic. Biol. Med. 26(7-8):887-91 (Apr, 1999).
6. Cirkovic, M. M., Bradbury, R. J., "Galactic Gradients, Postbiological Evolution and the Apparent Failure of SETI," [astro-ph/0506110] (June, 2005), submitted.

1. Bradbury, R. J., "Under Construction: Redesigning the Solar System", Chapter 7, pp 144-167 in Year Million, Damien Broderick (ed.), Atlas & Co. (2008).
2. Bradbury, R. J., "Life at the Limits of Physical Laws", SPIE 4273-32 OSETI III (Jan 2001). [Preprint:  PS format]
3. Bradbury, R. J., "Dyson Shells: A Retrospective", SPIE 4273-27 OSETI III (Jan 2001). [Preprint: PS format]
4. Bradbury, R., "Life at the Limits of Physical Laws",  "Frontiers of Life" (XIIèmes Rencontres de Blois) 25 June - 1st July, 2000.

1. R. A. Freitas Jr., "Microbivores: Artificial Mechanical Phagocytes using Digest and Discharge Protocol," Zyvex Publication (March 2001).  [local copy]
2. R. A. Freitas, "Some Limits to Global Ecophagy by Biovorous Nanoreplicators with Public Policy Recommendations" (May, 2000).
3. Nanomedicine: Volume I: Basic Capabilities, Robert A. Freitas, Jr., Landes Bioscience (1999).
4. R. A. Freitas, "Respirocytes: A Mechanical Artificial Red Cell: Exploratory Design in Medical Nanotechnology" (1999).
5. Nanomedicine: Volume IIA: Biocompatibility,  Robert A. Freitas, Jr., Landes Bioscience (1999).

1. Bradbury, R., "Life at the Limits of Physical Laws", presentation at "Frontiers of Life" (XIIèmes Rencontres de Blois) 25 June - 1st July, 2000.
2. Bradbury, R., "Microlensing meets SETI: Observations of evolutionary endpoints?", Microlensing 2000, Cape Town, South Africa, 21-25 February 2000.
3. Bradbury, R., "Dyson Shell Supercomputers as the Dominant 'Life Form' in Galaxies", Bioastronomy 99: A New Era in Bioastronomy, Kohala Coast, Hawaii, 2-6 August 1999.

1. "Biotechnology & Nanomedicine: Molecular Technologies for the Extension of Life", presentation to the Medical Technology Interest Group (MTIG) of the Medical School and Wharton School of Business at the University of Pennsylvania, November  6, 2000.
2. "Nanomedicine - Molecular Technology for the Extension of Life", Physicians CME seminar at the Valley Regional Medical Center in Brownsville, Texas,  July 20, 2000.
3. "Genomes, Biobots and Nanobots: Implications for 21^st Century Medicine", 7th International Conference on Anti-Aging and Biomedical Technologies, December 11-13, 1999.
4. "Genomes, Biobots and Nanobots: Implications for 21^st Century Medicine", Extro4, August 7-8, 1999.
5. "Paths to Immortality", presentation Extro3, August 9-10, 1997.

• Circa 1978-1979, in conjunction with Forrest Howard, wrote a PDP-10 simulator that ran on a PDP-11/70 computer. This allowed the compilation of the DEC PDP-11 Fortran compiler (written in Bliss-11) on a PDP-11 (minicomputer) rather than a PDP-10 (mainframe). The simulation of a PDP-10 with 36-bit words, on a PDP-11 with 16-bit words required more than an insignificant amount of ingenuity.

 
• Circa 1981-1983, adapted the Yourdon C-compler to several computer architectures including the IBM Series-1 and System 370 and the National Semiconductor 16000 chip.

 
• From 1982-1988 was responsible for the adaptation of the Oracle Relational Database management system to more than 10 different computer hardware and operating system combinations. Was responsible for the development of the tools that ensured the portability of the Oracle Relational Database Management system across a variety of systems.

 
• During 1985-1987, participated in the ANSI X3J11 committee to standardize the C programming language. Several library function specifications (memmove, memcpy) were a direct result of my contributions.

 
• Establishing the Aeiveos Corporation Research Library Web Site (www.aeiveos.com). Since 1993, before most people had heard of the "WWW", this has been one of the largest collections of information related to aging and longevity available to researchers and the public.  Development of the Aeiveos Library was terminated circa 1998 because other larger organizations (e.g. The National Library of Medicine, The Life Extension Foundation and eMedicine.com) fulfilled many of the functions the Aeiveos Library previously fulfilled.

 
• From 1992-1995, established a number of collaborations with Russian research groups involving gene cloning, differential gene expression studies, the creation of transgenic animals for bioreactors, dietary supplement studies directed towards the reduction of DNA damage and the development of high throughput DNA sequencing devices. A patent was secured on methods for the transformation of the mammary glands of animals for the production of foreign proteins.

 
• Founding, securing $8 million in financing for, and managing successfully through the initial startup phases, Aeiveos Sciences Group. During 1996 and 1997, ASG was the second largest company doing research in the molecular biology of aging (after Geron Corporation).  The scientific advisory board for ASG included noted professionals in the field of aging and biomedical research, including Dr. Stuart Aaronson, Dr. Steven Austad, Dr. Ranajit Chakraborty, Dr. George Martin, Dr. Michael McClelland and Dr. Robert Robbins, and Dr. Jan Vijg. ASG was a pioneer in the exploration of the genetics of aging (genotyping) and studies of differential gene expression in aging.  ASG ceased operations in early 1998 due to uncertainties regarding the property rights on genes derived from the human genome and the improper timing regarding the methods and scale of research required to understand and develop interventions in age-related pathologies.

 
• From 1997-2001, developed the concepts involved in a realistic supercomputer architecture spanning solar system sized scales, constructed using molecular nanotechnology (a Matrioshka Brain). Educated scientists such as those involved in the exploration of currently unexplained astronomical phenomena and those searching for extraterrestrial civilizations regarding the probable forms that advanced technological civilizations will adopt.

 
• From 2001-2003, developed a business plan and started Robiobotics, LLC to accomplish the development of "whole genome engineering" and attempted to obtain in excess of $10 million in private financing for this effort.  Due to the poor financial markets it proved impossible to secure financing.  During this period several other NIH and DOE funded companies were able to secure funding for similar purposes.  It is my belief that such technologies will be necessary to address both retarding the rate of aging as well as potentially reduce the damage caused by the cryonics freezing processes.